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KMID : 0359920070260060744
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Korean Journal of Nephrology
2007 Volume.26 No. 6 p.744 ~ p.747
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A Case of Rhabdomyolysis and Acute Renal Failure Associated with Primary Hypothyroidism
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Woo Myoung-Lyeol
Lee Seung-Won
Choi Ja-Sung
Won Young-Jun
Yoon Soo-Young
Lee Sang-Choel
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Abstract
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Hypothyroidism is a clinical state which results from decreased production of thyroid hormone, and its symptoms are various including lack of energy, dryness of skin and hair, dyspnea, bradycardia, hypotension, body weight gain, and constipation. Muscle disorders due to hypothyroidism may include myalgia, muscle weakness, stiffness, delayed tendon reflex, abnormality of electromyography, changes of muscle tissues and increased muscle enzymes. Hypothyroid myopathy manifests as a mild form of myopathy rather than an acute rhabdomyolysis, that is a very rare complication of hypothyroid myopathy and that can cause acute renal failure.
We report a case of primary hypothyroidism presented with rhabdomyolysis and acute renal failure. A 50-year-old male referred to our hospital for evaluation and management of generalized edema, muscle weakness, fatigue and myalgia. He had acute rhabdomyolysis and progressed to acute renal failure due to newly developed primary hypothyroidism. After hormone replacement therapy with levothyroxine, the patients renal function and muscular symptom completely recovered.
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KEYWORD
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Acute renal failure, Hypothyroidism, Rhabdomyolysis, Myopathy
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